Pure Skin: Most Common Side Effects of Weight Loss Injections: What to Expect with Tirzepatide
The Most Common Side Effects of Weight Loss Injections | Pure Skin

The Most Common Side Effects of Weight Loss Injections—and How to Manage Them

GLP-1 weight loss injections like Tirzepatide have helped thousands lose weight safely and effectively—but like all medications, they can come with a few side effects. At Pure Skin, we prioritize education and comfort, so here’s what you need to know if you’re starting treatment.

1. Nausea: The Most Reported Side Effect

Nausea is the most common issue clients report when starting Tirzepatide. It typically occurs in the first few doses and often resolves as your body adjusts. Eating smaller, protein-rich meals and staying hydrated can help ease discomfort.

2. Digestive Upset: Vomiting, Diarrhea, or Indigestion

Some patients experience mild gastrointestinal symptoms like vomiting, diarrhea, or indigestion. These are generally short-lived and can often be prevented or treated with OTC remedies or simple dietary tweaks.

3. Constipation: Stay Ahead of It

Constipation is another frequent complaint, especially if you're not drinking enough water. We recommend increasing fiber intake, using natural remedies like magnesium, or speaking to your provider for safe, gentle solutions.

4. These Side Effects Are Usually Temporary

Most symptoms are short-term and manageable. As your dose is gradually increased, side effects typically fade. Many clients report that once the initial adjustment period passes, they feel significantly better and experience greater appetite control.

5. Talk to Your Provider for Support

If symptoms become persistent or interfere with daily life, our providers at Pure Skin are here to help. From adjusting your dosage to recommending the right support products, we’re with you every step of the way.

Conclusion: While weight loss injections like Tirzepatide can cause nausea or constipation early on, most side effects are mild and manageable. With the right care and education, you can stay on track—and stay comfortable—through your weight loss journey.

Contact Us

Read More

Finding Balance Again: Lynley's Journey with Hormone Replacement Therapy (HRT)
January 15, 2026
Discover how HRT helped Lynley, our Southington Coordinator, regain mental clarity, energy, and well-being. Learn what to expect and how personalized care makes all the difference.
HRT at Pure Skin
January 14, 2026
Becky overcame brain fog, fatigue, and poor sleep with personalized HRT at Pure Skin. Discover how hormone therapy helped her feel like herself again.
Feeling Like Myself Again: Christina’s HRT Journey with Pure Skin
January 14, 2026
At Pure Skin, our mission is to help you look and feel your best, inside and out. For Christina, that journey began when she realized something wasn’t quite right. Despite living a healthy lifestyle (eating well, exercising regularly, and taking care of her body) she still felt off. Depleted. Tired. Like she was doing everything right, but not getting the results she deserved. “I was feeling depleted and tired…brain fog, all of that,” Christina shared. “I just wasn’t feeling myself.” That’s when she turned to Pure Skin, a place she already trusted for her aesthetic needs from facials to Botox and beyond. This time, she came in for something different: hormone replacement therapy (HRT), specifically the HRT pellet treatment.
Who should not get botox or fillers ? a provider 's honest advice
August 7, 2025
Not everyone is a candidate for Botox® or fillers. Learn who should avoid injectables and why working with a qualified provider is key to safe, effective results.
August 7, 2025
Thinking about dermal fillers? Learn about the cost of fillers and the factors that contribute. Stay informed and choose safely with Pure Skin
August 7, 2025
Explore the most common BOTOX® injection sites like frown lines and crow’s feet. Learn what to expect during treatment and how it helps prevent and reduce wrinkles.
August 7, 2025
Discover the key differences between BOTOX® and dermal fillers with Pure Skin. Learn which treatment is right for your aesthetic goals and skin concerns.
August 7, 2025
What are the risks of BOTOX® and fillers? Stay informed and stay safe with the medical professionals at Pure Skin MedSpa.
August 7, 2025
Discover the best booty filler for enhancing volume, improving shape, and stimulating collagen. Learn how RADIESSE® delivers natural-looking, long-lasting results at Pure Skin.
August 7, 2025
Maximize the longevity of your BOTOX® and filler results with expert tips from Pure Skin. Learn how skincare, facials, and maintenance routines can extend your treatment benefits.
Show More